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Androgel

Androgel 1%, a 400% price increase:
How many men are affected by it?

by Charles H. Babb

Perhaps you recollect me. We met over the phone in 1996 or 1997 and shared stories before I became a subscriber. My tumor was 3 ½ cm, acromegaly. After a surgery and 26 subsequent stereotactic radiation treatments, my brain was burned in 14 areas. I am mostly recovered from that now, but lacking medical insurance. Now I must pay cash for annual endocrinological tests, bi-annual MRI’s, and my prescriptions.

In September of 2002 in California I learned that Androgel 1%, 5 grams, which I am prescribed for the rest of my life - had been repriced on the retail market with an amazing 400% mark-up, directly as the result of, it seems, a corporate buy-out. According to the stories of two knowledgeable pharmacists: “Early in 2002, Solvay Pharmaceuticals, Inc., having purchased Unimed Pharmaceuticals Inc., then selectively decided to reprice Unimed’s product AndroGel 1% metrically. Because each packet or unit dose contains 5 grams, the new price became five times the old price”. The price immediately jumped from $38. to $189 per quantity of 30. “AndroGel” is synthetic testosterone and a controlled substance, hence not available through foreign markets, although Canadian suppliers of minimum cosmetic quantities of testosterone may also have repriced.

While I may assume that most male pituitary tumor patients require permanent hormone replacement therapy, I really do not know how many of us there might be, captive in this situation. Because of the successful surgical removal of my pituitary tumor –and most of my pituitary gland– ongoing hormonal replacement therapy is now a necessity, and the hormonal drug testosterone is essential. The Pituitary Network Association Website presents a Pituitary Patient’s Bill of Rights. Under this doctrine, would not the fact that Unimed previously made a fine profit on “AndroGel”, before any buy-out, be recognized -- and Solvay’s metric repricing scheme be considered, at the very least, somewhat unethical? Perhaps this should be looked into, especially if many of us are affected.

As a totally unforeseen consequence of the forementioned successful surgery, I became uninsurable. My monthly premiums jumped from $125 to $950 per month within four years. Thus at age 56, I have become a “cash payee”. A 400% increase is simply unaffordable. I can’t believe that I am alone in this dilemma. Can the resources of the Pituitary Network Association help me to determine the number of men like myself who are thus affected? How many male pituitary patients, and their insurers, must bear this artificially created and greatly amplified cost?

As a class, we are impacted by decisions of both insurance companies and pharmaceutical manufacturers. Manufacturer’s decisions made arbitrarily to increase the price of medications directly affects our insurer’s costs. And, we are unrepresented as a class, unlike other victim’s of better known diseases. Will you help me accurately determine the current and projected numbers of pituitary patients on testosterone replacement?


Last Revised : June, 2005





Real Financial Value of a Good Endocrinologist
By Robert Knutzen

It strikes us as absurd  that we even feel compelled to write this piece of personal opinion.  Sadly, it is even more absurd that the hospital/university/medical center administrators and chiefs of internal medicine across the world has such little understanding of the value of the pituitary endocrinologists on their staffs that they continuously undercut the operating budgets and the staffs of these departments and divisions because they are not “profit-centers”.

Allow us please to strongly disagree and share with you the basis for this opinion. Even in major university hospitals (and we know where they are) the pituitary endocrine staffs are kept at a minimum and in some it is only considered part time work to be shared with diabetes care.

Allow us, since we know first hand, to recite but some of the  associated disorders and medical needs faced by an average pituitary patient and managed by a GOOD pituitary endocrinologist.  (Yes, some of us DO find our way to good endocrine care, no thanks to the Deans of Medical Schools who clearly, in many cases, do a very substandard job of teaching the basics of physiology and endocrinology to their medical students and nurses; we do not know where they teach it well enough to do their students, society and the patients much good).

The scenario is pretty much as outlined-give or take a few fiasco’s here and there:  First the patients spend an inordinate amount of time looking for a diagnosis in all the wrong places.  To the insurance companies and  HMO’s this ignorance is apparently acceptable, mostly we suppose, because it is cheaper NOT to find anything wrong and therefore not having to treat life-altering and often life-shortening disease(s).  Any GOOD pituitary endocrinologist, over a cold beer, will tell you that it is  NOT  that difficult to diagnose most pituitary disorders, IF you have a reasonable level of suspicion.  Since we (the pituitary patients) constitute between 20 and 30 % of the world’s population, therefore the same percentage of the average physicians patients, it is impossible to hide behind “rare”.  That excuse died an ignominious death many years ago. 

Secondly, the patient has asked for help at OB/GYN’s, family practitioners, urologists, rheumatologists, orthopedists, dermatologists, psychologists, psychiatrists, optometrists, opthalmologists, herbalists, acupuncturists, chiropractors and virtually anyone else who promises help and healing (It is interesting that they may be referred, again, to many of the same specialists AFTER diagnosis, and the same doctor now says, Ah Ha, Now we know what to treat you for). Finally, one of the above, or a family member, a hairdresser or a dentist or shoe-salesman will finally direct the patient to an endocrinologist.  The patient (not often enough) will start asking questions, and, not getting satisfactory answers, will find his or her way to a pituitary center.

Thirdly, and here is the rub, most experts are booked months or at least weeks in advance. He or she, the expert, is overworked, overwhelmed and under-appreciated. Now, the core:  A) The endocrinologist starts with a series of tests; the financial beneficiary - the laboratory (in house or outside).  B) An MRI scan; the financial beneficiary - the scanning lab or radiology department. (In house or outside). C) An opthalmological scan; the financial beneficiary - the dept. of opthalmology. D) A bone density scan; the financial beneficiary - the orthopedic division or a separate laboratory or scanning center.  E) A colonoscopy; the financial beneficiary - the dept. of gastroenterology.

Now we start treatment:

A) Prescriptions for medications and/or hormone replacement; the financial beneficiary - the pharmacy and the pharmaceutical industry.  B) Neurosurgery; the beneficiary - the department of neurosurgery. In many cases this is followed by radiosurgery or other radiation treatment; the beneficiary - departments of neurosurgery/skull based surgery and or the department of nuclear medicine/radiation.   And, lest we forget, the hospital STAY; financial beneficiary - the hospital/medical center directly.  As we all know, this may be accompanied by other tests or surgeries or treatment, all usually directed to other departments or divisions by none other than the overworked and under-appreciated endocrinologist who “puts food” on everyone’s table but is considered a COST center in his/her own university or medical center.

The absurdity of the situation must be appreciated by anyone who can read, add and multiply: The pituitary endocrinologist is potentially a MAJOR PROFIT CENTER for everyone  associated or affiliated with the department of endocrinology in all major hospitals/medical centers.  In a law practice he/she would be called a “rainmaker”.  To the patients and families they are considered a God-send. 

Can we please start an economics course for hospital administrators?  We, the patients, need it to insure a ready supply of eager, willing and capable pituitary endocrinologists to care for us!  And our numbers grow, every day.